What is considered a safe level of aluminum contamination in generator eluate for radiopharmaceuticals?

The safe level of aluminum contamination in generator eluate for radiopharmaceuticals is defined as being below 10 µ/mL. This standard is important because aluminum can interfere with the stability and efficacy of radiopharmaceuticals, potentially impacting patient safety and treatment outcomes. Below this threshold, the risk of adverse effects related to aluminum contamination is considered acceptable.

In practice, maintaining aluminum levels below this limit helps ensure that the radiopharmaceuticals administered to patients retain their intended biological activity and minimize the risk of toxicity. Understanding and adhering to these limits is vital for quality control in radiopharmacy and ensures compliance with regulatory guidelines.