Why is the quality assurance for SPECT gamma cameras more demanding compared to planar gamma cameras?

Quality assurance for SPECT gamma cameras is indeed more demanding primarily because nonuniformity issues can amplify significantly in SPECT imaging. SPECT cameras utilize multiple rotating detectors and create three-dimensional images by acquiring data from various angles. This process inherently increases the potential for detecting and amplifying nonuniformities in the system, such as variations in detector sensitivity and variations in image reconstruction algorithms.

These artifacts can lead to significant errors in the quantification and localization of radiotracer distributions, ultimately affecting diagnostic accuracy. Therefore, rigorous quality control measures are essential to identify and correct any nonuniformities that could compromise the image quality or the reliability of the diagnostic results produced by SPECT.

In contrast, planar gamma cameras typically have a more straightforward imaging approach, which makes them less prone to the complexities associated with simultaneous multi-angle acquisitions and reconstruction processes. Hence, the severity and impact of nonuniformity are more pronounced in SPECT, necessitating heightened quality assurance efforts.